ncRNA name | BDNF-AS |
ncRNA Category | lncRNA |
ID | 497258 |
Ensembl | ENSG00000245573 |
Synonyms | BDNF-AS1, BDNFAS, BDNFOS, BT2A, BT2B, BT2C, BT2D, NCRNA00049 |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | apoptosis assay, qRT-PCR, Western blot |
Expression pattern | up-regulated |
Functional description | Our results suggest that BDNF-AS, through inverse regulation of BDNF, might play a critical role in the process of DGI apoptosis in diabetic retinopathy. |
PubMed ID | 28657668 |
Year | 2018 |
Title | Long noncoding RNA BDNF-AS inversely regulated BDNF and modulated high-glucose induced apoptosis in human retinal pigment epithelial cells. |
Drug-related ncRNA | NO |
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