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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name BDNF-AS
ncRNA Category lncRNA
ID 497258
Ensembl ENSG00000245573
Synonyms BDNF-AS1, BDNFAS, BDNFOS, BT2A, BT2B, BT2C, BT2D, NCRNA00049
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human RPE cell line ARPE-19
Methods apoptosis assay, qRT-PCR, Western blot
Expression pattern up-regulated
Functional description Our results suggest that BDNF-AS, through inverse regulation of BDNF, might play a critical role in the process of DGI apoptosis in diabetic retinopathy.
PubMed ID 28657668
Year 2018
Title Long noncoding RNA BDNF-AS inversely regulated BDNF and modulated high-glucose induced apoptosis in human retinal pigment epithelial cells.
Drug-related ncRNA NO

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